Consequently, triazolam should be avoided in patients receiving very potent inhibitors of CYP 3A.
The elderly are especially susceptible to the dose related adverse effects of Halcion.
Protect from light.
Patients should be instructed to discontinue the drug prior to becoming pregnant.
Observational studies have demonstrated that concomitant use of opioid analgesics and benzodiazepines increases the risk of drug-related mortality compared to use of opioids alone.
Previously Cosby had said that he received prescriptions for Quaaludes decades prior.
Because some of the important adverse effects of sedative-hypnotics appear to be dose related see Precautions and Dosage and Administrationit is important to use the smallest possible effective dose, especially in the elderly.
Physical and psychological dependence is not the same as drug addiction.
Therefore, administration of Halcion to nursing mothers is not recommended.